曲霉菌病
Aspergillosis
定义 英文原文（暂无中文）
A rare infectious disease caused by inhalation of the opportunistic fungus aspergillus that can lead to the following manifestations: allergic bronchopulmonary aspergillosis (ABPA), aspergilloma, chronic necrotizing pulmonary aspergillosis (CNPA), and invasive aspergillosis (IA). Aspergilloma occurs in patients with cavitary lung disease and results in a fungal mass with variable clinical presentations from asymptomatic to life-threatening (massive hemoptysis). CNPA manifests as subacute pneumonia in patients with underlying disease. IA is disseminated aspergillosis that eventually invades other organs. Cutaneous aspergillosis is usually the dermatological manifestation of IA that manifests as erythematous-to-violaceous plaques or papules, often characterized by a central necrotic ulcer or eschar.
基本事实
- 遗传方式
- 不适用
- 发病年龄
- 各年龄段
临床表型 56
极常见 99–80%2
- 咳嗽 HP:0012735
- 血液(1-3)-β-葡聚糖检测阳性 HP:0020153
常见 79–30%12
- 痰液异常 HP:0032016
- 肺功能检测结果异常 HP:0030878
- 胸痛 HP:0100749
- 慢性肺病 HP:0006528
- 中性粒细胞减少症 HP:0001875
- 发热 HP:0001945
- 毛玻璃样结构 HP:0025179
- 咯血 HP:0002105
- 免疫缺陷 HP:0002721
- 嗜酸性粒细胞增多症 HP:0001880
- 肺实变 HP:0032177
- 肺浸润 HP:0002113
偶见 29–5%25
- 食管形态结构异常 HP:0002031
- 心血管系统的任何异常。 HP:0001626
- 肾脏异常 HP:0000077
- 哮喘 HP:0002099
- 慢性阻塞性肺疾病 HP:0006510
- 泪囊炎 HP:0000620
- 弥漫性网状或细结节状浸润 HP:0002207
- 呼吸困难 HP:0002094
- 头痛 HP:0002315
- 血液肿瘤 HP:0004377
- 肝炎 HP:0012115
- 过敏性肺炎 HP:0006516
- 免疫过敏 HP:0100326
- 循环IgE水平升高 HP:0003212
- 侵袭性肺曲霉菌病 HP:0020103
- 角膜炎 HP:0000491
- 局限性皮损 HP:0011355
- 鼻塞 HP:0001742
- 眼痛 HP:0200026
- 胸膜炎 HP:0002102
- 肺炎 HP:0002090
- 肺纤维化 HP:0002206
- 鼻溢液 HP:0031417
- 鼻窦炎 HP:0000246
- 视觉障碍 HP:0000505
罕见 <4–1%17
- 肋骨形态异常 HP:0000772
- 气管支气管系统形态异常 HP:0005607
- 长骨形态异常 HP:0011314
- 颅底形态异常 HP:0002693
- 脊柱异常 HP:0000925
- 支气管扩张 HP:0002110
- 功能性运动障碍 HP:0004302
- 传染性脑炎 HP:0002383
- 颅内出血 HP:0002170
- 脑膜炎 HP:0001287
- 骨髓炎 HP:0002754
- 眶周丰满 HP:0000629
- 胸腔积液 HP:0002202
- 癫痫发作 HP:0001250
- 卒中 HP:0001297
- 不寻常的中枢神经系统感染 HP:0011450
- 玻璃体炎 HP:0011531
外部标识与链接
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本页数据来源
- 疾病定义、同义词、基因、表型、流行病学：Orphanet（CC BY 4.0）
- 中文病名：Orphanet 中文包，冻结于 2020-06-01
- 表型中文标签：HPO 简体中文翻译（CHPO 上游成果）