孤立性肌张力障碍

别名

单纯型肌张力障碍

相关基因 13来自下位疾病

Orphanet 未在本条目上直接标注致病基因。下表由本组所属的下位疾病汇总而来，「来源条目」列给出基因实际标注在哪一个 ORPHA 条目上。

近两年的全球研究 151L2

2024/08 起在 Europe PMC 检索所得，按发表时间倒序显示最近 20 篇。标题未译成中文——自动翻译需要接入 LLM 服务，尚未引入。

• 2026-08
  Reluctance to Video Recording in Functional Movement Disorders: A Cross-Sectional Study
  Brain and behavior · DOI · Europe PMC
• 2026-06
  Clinical and Genetic Spectrum of ANO3-Related Dystonia with Treatment Responses in a Chinese Cohort
  Genes · DOI · Europe PMC
• 2026-06开放获取
  Clinical and Genetic Spectrum of ANO3-Related Dystonia with Treatment Responses in a Chinese Cohort
  Genes
• 2026-05开放获取
  Highlighting the value of polymyography in childhood onset movement disorders
  Frontiers in neurology · DOI · Europe PMC
• 2026-05开放获取
  Correlation between electrode location and clinical efficacy of deep brain stimulation of the globus pallidus internus in isolated generalized dystonia
  Frontiers in neurology · DOI · Europe PMC
• 2026-05开放获取
  Clinical Phenotype Comparison in Polish Patient Cohorts with and Without Molecular Diagnosis of Dystonia
  Journal of clinical medicine · DOI · Europe PMC
• 2026-05综述开放获取
  Artificial Intelligence in Botulinum Toxin Injections: A Mini-Review of Current Applications, Challenges, and Translational Perspectives
  Cureus · DOI · Europe PMC
• 2026-05开放获取
  Deep brain stimulation for the treatment of paediatric dystonia due to neuroanatomical abnormalities: a systematic review of efficacy and future perspectives
  BMJ neurology open · DOI · Europe PMC
• 2026-05开放获取
  Trihexyphenidyl Ameliorates Depression-like Behaviors in Adult Zebrafish Exposed to Chronic Unpredictable Stress, Consistent with Regulation of the MAPK Signaling Pathway
  Biomolecules · DOI · Europe PMC
• 2026-05
  Multicenter validation of the Italian Pain in Dystonia Scale in idiopathic adult-onset cervical dystonia
  Neurological sciences : official journal of the Italian Neurological S · DOI · Europe PMC
• 2026-04开放获取
  Correlation Between Electrode Location and Clinical Efficacy of Deep Brain Stimulation of the Subthalamic Nucleus in Isolated Generalized Dystonia
  Journal of clinical medicine · DOI · Europe PMC
• 2026-04系统综述综述开放获取
  Clinical efficacy of neuromodulation in isolated dystonia: A systematic review of motor function improvement
  Neurological sciences : official journal of the Italian Neurological S · DOI · Europe PMC
• 2026-04开放获取
  Shared and distinct dynamic brain activity and functional connectivity variability in patients with isolated craniocervical dystonia
  Brain communications · DOI · Europe PMC
• 2026-03
  Reply: "Segmental vs. Multifocal: The 2025 Dystonia Classification Is Helpful"
  Movement disorders clinical practice · DOI · Europe PMC
• 2026-03综述开放获取
  Proceedings of the 13th annual deep brain stimulation think tank: the evolving landscape
  Frontiers in human neuroscience · DOI · Europe PMC
• 2026-02综述开放获取
  Deep brain stimulation in children with acquired dystonia
  Frontiers in neurology · 被引 1 · DOI · Europe PMC
• 2026-02开放获取
  Multimodal MRI reveals structural and functional alterations in isolated cervical dystonia: associations with motor severity and affective symptoms
  Frontiers in neurology · DOI · Europe PMC
• 2026-02
  The Pain in Dystonia Scale (PIDS)-Validation in Craniofacial and Upper Limb Dystonia
  Movement disorders clinical practice · DOI · Europe PMC
• 2026-02开放获取
  Effects of Deep Brain Stimulation on Adductor Laryngeal Dystonia
  The Laryngoscope · DOI · Europe PMC
• 2026-02综述病例报告
  DYT-AOPEP: A case series from India expanding the clinical and genetic spectrum
  Parkinsonism & related disorders · DOI · Europe PMC

在中国开展的临床试验 1L2

按病名在 ClinicalTrials.gov 检索、并校验研究中心含中国大陆而来。登记状态不等于现在真的能入组——务必按 NCT 号到原站核实，并与主治医生商量。

当前没有检索到登记为可入组的试验。

中国境外的在招试验 3L2

共 4 项。

• 尚未开始招募NCT06792500
  A Basket Clinical Study to Assess Glycerol Tributyrate in Patients With Mitochondrial Encephalopathy, Lactic Acidosis, Stroke-like Episodes (MELAS) or Leber's Hereditary Optic Neuropathy-Plus (LHON-Plus)
  I 期、II 期 · 干预性 · 2026/10George Washington University
  美国
• 招募中NCT07304089
  A Study to Evaluate the Efficacy, Safety, and Tolerability of VIM0423 in Individuals With Isolated Dystonia
  II 期 · 干预性 · 2026/02/05Vima Therapeutics
  美国
• 招募中NCT07111663
  An Observational Study of Individuals With Isolated Dystonia
  观察性 · 2025/06/17Vima Therapeutics
  美国
• 招募中NCT05317390
  Clinical Validation of DystoniaNet Deep Learning Platform for Diagnosis of Isolated Dystonia
  不适用 · 干预性 · 2022/06/01Massachusetts Eye and Ear Infirmary
  美国

外部标识与链接