吲哚美辛胚胎胎儿病

定义 英文原文（暂无中文）

Indomethacin embryofetopathy refers to the manifestations that may be observed in a fetus or newborn when the mother has taken indomethacin, a potent prostaglandin inhibitor and tocolytic agent that can cross placenta, during pregnancy. Reported adverse fetal/neonatal effects include decreased renal function resulting in oligohydramnios, closure of the ductus arteriosus, and delayed cardiovascular adaptation at birth. These effects are usually transient and reversible. Indomethacin may also be a risk factor for cerebral injury (periventricular leukomalacia) and necrotizing enterocolitis in preterm infants.

别名

胎儿吲哚美辛综合征

基本事实

遗传方式

不适用

发病年龄

产前、新生儿期

临床表型 12

外部标识与链接