嗜酸细胞性胃肠炎

定义 英文原文（暂无中文）

A rare benign gastrointestinal disease characterized by the presence of abnormal and nonspecific gastro-intestinal (GI) manifestations, associated with an eosinophilic infiltration of the GI tract, which can affect several segments and involve several layers within the GI wall.

别名

嗜酸细胞性胃小肠结肠炎

基本事实

遗传方式

不适用

发病年龄

各年龄段

患病率

1-9 / 100 000

临床表型 21

近两年的全球研究 270L2

2024/10 起在 Europe PMC 检索所得，按发表时间倒序显示最近 20 篇。标题未译成中文——自动翻译需要接入 LLM 服务，尚未引入。

• 2026-10
  Abstracts
  JPGN reports
• 2026-09开放获取
  A Retrospective Review of 1821 Cases of Eosinophilia in a Single-Center Study in Eastern China
  EJHaem · DOI · Europe PMC
• 2026-09综述开放获取
  Understanding Tryptase Physiology, Clinical Significance, and Diagnostic Applications: Where Do We Stand?
  Biomolecules · DOI · Europe PMC
• 2026-09病例报告开放获取
  Multiple Deep Abscesses Caused by Disseminated <i>Nocardia farcinica</i> Infection After Immunosuppressive Treatment for Membranous Nephropathy: A Case Report and Literature Review
  Infection and drug resistance · DOI · Europe PMC
• 2026-09综述开放获取
  Cronkhite-Canada syndrome: An elusive gastrointestinal disorder with multisystem involvement-pathogenesis, diagnosis, and therapeutic strategies
  World journal of gastrointestinal pathophysiology · DOI · Europe PMC
• 2026-09
  Correlation Analysis Between Increased CD63 Expression Detected by Eosinophil Activation Test and sIgE Levels
  Scandinavian journal of immunology
• 2026-08综述开放获取
  Evidence-Based Clinical Recommendations on the Appropriateness of Prescriptions and Diagnostic Tests in Paediatric Allergology: Focus on IgE-Mediated and Non-IgE Mediated Food Allergy, Eosinophilic Gastrointestinal Disease, Urticaria, Angioedema and Atopic Dermatitis
  Children (Basel, Switzerland) · DOI · Europe PMC
• 2026-08综述开放获取
  Evidence-based clinical practice guidelines for peptic ulcer disease 2026
  Journal of gastroenterology · DOI · Europe PMC
• 2026-08开放获取
  Isolated rectal bleeding in neonates: a scoping review
  Jornal de pediatria · DOI · Europe PMC
• 2026-08
  Clinical Characteristics, Diagnostic Challenges, and Therapeutic Outcomes in Non-eosinophilic Esophagitis Eosinophilic Gastrointestinal Diseases in Comparison with Eosinophilic Esophagitis
  Iranian journal of allergy, asthma, and immunology · DOI · Europe PMC
• 2026-08开放获取
  Clinical Analysis of 17 Cases of Eosinophilic Cystitis in Children and Literature Review
  Pediatric health, medicine and therapeutics · DOI · Europe PMC
• 2026-08病例报告开放获取
  Multifocal Giant Granular Cell Tumors of the Alimentary Canal With Concurrent Eosinophilic Gastrointestinal Disease
  ACG case reports journal · DOI · Europe PMC
• 2026-08综述开放获取
  Emerging Insights into the Inflammatory Phenotypes of Eosinophilic Esophagitis
  Journal of inflammation research · DOI · Europe PMC
• 2026-08病例报告开放获取
  Duodenal Strongyloidiasis Mimicking Inflammatory Bowel Disease: A Case Report of a 52-Year-Old Immunocompetent Woman
  Clinical medicine insights. Case reports · DOI · Europe PMC
• 2026-08
  [Analysis of clinical characteristics and factors associated with recurrence in children with eosinophilic gastroenteritis]
  Zhonghua yi xue za zhi · DOI · Europe PMC
• 2026-07病例报告开放获取
  Eosinophilic Duodenitis and Jejunitis with Ascites and Peripheral Eosinophilia: A Diagnostic Challenge-Case Report
  Life (Basel, Switzerland) · DOI · Europe PMC
• 2026-07开放获取
  Evidence-based, cost-effective management of gastric outlet obstruction: An algorithm of the Journal of Trauma and Acute Care Surgery , Emergency General Surgery Algorithms Work Group
  The journal of trauma and acute care surgery · DOI · Europe PMC
• 2026-07开放获取
  Esophageal Involvement in Non-Eosinophilic Esophagitis Eosinophilic Gastrointestinal Diseases: Association With Esophageal Symptoms and Gastric Involvement
  JGH open : an open access journal of gastroenterology and hepatology · DOI · Europe PMC
• 2026-07开放获取
  Outcomes of Dupilumab Treatment in Refractory Eosinophilic Esophagitis: A Retrospective Cohort Study from Saudi Arabia
  Saudi journal of medicine & medical sciences · DOI · Europe PMC
• 2026-07
  Eosinophilic gastroenteritis due to egg allergy in a 70-year-old patient
  Revista espanola de enfermedades digestivas · DOI · Europe PMC

在中国开展的临床试验 2L2

按病名在 ClinicalTrials.gov 检索、并校验研究中心含中国大陆而来。登记状态不等于现在真的能入组——务必按 NCT 号到原站核实，并与主治医生商量。

登记为可入组 1

• 招募中NCT07257835
  Dupilumab Therapy for EGIDs
  观察性 · 2025/01/01Children's Hospital of Fudan University
  中国研究中心 1 个：Shanghai

中国境外的在招试验 43L2

CT.gov 报告命中 43 项，此处取回并展示最近的 15 项。

• 尚未开始招募NCT07023380
  EoE Food Test Pilot Study
  不适用 · 干预性 · 2027/01/01Children's Hospital of Philadelphia
  美国
• 尚未开始招募NCT07588568
  A Trial of Upadacitinib for Non-responsive Eosinophilic Esophagitis
  II 期 · 干预性 · 2026/10University of North Carolina, Chapel Hill
  美国
• 招募中NCT07027826
  The Esophageal String Test as a Diagnostic Screening Tool for Eosinophilic Esophagitis Among Africans With Dysphagia in Mali and the United States
  不适用 · 干预性 · 2026/09/23National Institute of Allergy and Infectious Diseases (NIAID)
  Mali、美国
• 招募中NCT07780981
  Impact of Body Positioning on EndoFLIP Measurements: A Comparative Study of Supine and Left Lateral Decubitus Positions
  不适用 · 干预性 · 2026/07/24Johns Hopkins University
  美国
• 招募中NCT07779772
  Elimination Diet Strategies and Histologic Remission in Children With Eosinophilic Gastrointestinal Disorders
  观察性 · 2026/07/01Cukurova University
  土耳其
• 招募中NCT07234825
  Trial of Partial Enteral Nutrition With Dairy Free Diet in Eosinophilic Esophagitis
  不适用 · 干预性 · 2026/03/18Kate Farms Inc
  美国
• 招募中NCT07506746
  PRospective Registry of Esophageal Motility
  观察性 · 2026/03/09IRCCS San Raffaele
  意大利
• 招募中NCT07227506
  Utility of Mucosal Impedance Device in Chronic Esophageal Disorders:
  观察性 · 2025/11/20Medical College of Wisconsin
  美国
• 招募中NCT07112378
  A Study of Dupilumab in Small Children With an Allergic Condition of the Esophagus (Food Pipe): Eosinophilic Esophagitis
  III 期 · 干预性 · 2025/11/10Regeneron Pharmaceuticals
  美国
• 招募中NCT07614633
  Natural History of Eosinophilic Esophagitis in Adult and Pediatric Population
  观察性 · 2025/09/01Fondazione IRCCS Policlinico San Matteo di Pavia
  意大利
• 尚未开始招募NCT07057986
  Trans-Cervical and Trans-abdominal Ultrasound for Monitoring Esophageal Thickness in Eosinophilic Esophagitis
  不适用 · 干预性 · 2025/08/01Sheba Medical Center
• 招募中NCT06972147
  Prevalence and Description of FIRE (Food Induced Immediate Response of the Esophagus) in the Pediatric Population With Eosinophilic Esophagitis
  观察性 · 2025/07/01University Hospital, Angers
  法国
• 招募中NCT07012928
  Local Clinical and Immunological Responses in Eosinophilic Esophagitis (EoE) Patients, Role of Mucosal Barrier Function and Type II Inflammation
  观察性 · 2025/07Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
  荷兰
• 尚未开始招募NCT06995274
  Umbilical Cord Blood Therapy in a Child With Eosinophilic Duodenitis and Autism Spectrum Disorder: a Case Study
  不适用 · 干预性 · 2025/06/01Bundang CHA Hospital
• 招募中NCT06695897
  A Non-interventional Observational Study to Assess Long-term Efficacy and Safety of Dupilumab for the Treatment of Patients (>= 12 Years) With Eosinophilic Esophagitis Under Real-world-conditions in Germany
  观察性 · 2025/05/28Sanofi
  德国

外部标识与链接