肾移植后新发血栓性微血管病
De novo thrombotic microangiopathy after kidney transplantation
定义 英文原文（暂无中文）
A rare renal disease characterized by thrombotic microangiopathy developing de novo in kidney transplant recipients with no evidence of occurrence of the disease prior to transplantation. Precipitating factors include antibody-mediated rejection, immunosuppressive medication, viral infections, and genetic abnormalities in the complement cascade, among others. The condition most commonly occurs within the first 3-6 months post-transplantation. Clinical presentation is highly variable and ranges from a limited form confined to the kidney with relatively good prognosis to a systemic variant consisting of the classic triad of thrombocytopenia, microangiopathic hemolytic anemia, and acute kidney injury.
基本事实
- 发病年龄
- 各年龄段
相关基因 2
| 基因 | 名称 | 关联类型 |
|---|---|---|
| CFH | complement factor H | Biomarker tested in |
| CFI | complement factor I | Biomarker tested in |
外部标识与链接
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本页数据来源
- 疾病定义、同义词、基因、表型、流行病学：Orphanet（CC BY 4.0）
- 中文病名：Orphanet 中文包，冻结于 2020-06-01
- 表型中文标签：HPO 简体中文翻译（CHPO 上游成果）