脊髓灰质炎
Poliomyelitis
ORPHA:2912疾病
定义 英文原文(暂无中文)
A rare viral infection caused by any of three serotypes of wild human poliovirus (types 1, 2 and 3), which are part of the family of enteroviruses; and three serotypes of Sabin vaccine-derived polioviruses (types 1, 2 and 3) that have accumulated genetic changes and regained the ability to cause polio paralysis. wild type 2 and type 3 polioviruses have been certified eradicated, wild type 1 poliovirus continues to circulate in Pakistan and Afghanistan, and vaccine-derived polio viruses mainly circulate in sub-Saharan Africa.
基本事实
- 遗传方式
- 不适用
- 发病年龄
- 儿童期
- 患病率
- <1 / 1 000 000(Europe)
临床表型 53
极常见 99–80%2
- 肌无力 HP:0001324
- 疼痛 HP:0012531
常见 79–30%24
- 运动神经传导速度异常 HP:0040131
- 骨骼肌形态异常 HP:0011805
- 厌食症 HP:0002039
- 神经反射消失 HP:0001284
- 关节疼痛 HP:0002829
- 反射活跃 HP:0001348
- 运动不耐受 HP:0003546
- 疲乏 HP:0012378
- 发热 HP:0001945
- 功能性运动障碍 HP:0004302
- 头痛 HP:0002315
- 肌肉组织发育不全 HP:0009004
- 自卑 HP:0031469
- 下肢肌肉无力 HP:0007340
- 脑膜炎 HP:0001287
- 肌无力 HP:0010547
- 肌痛 HP:0003326
- 脊髓炎 HP:0012486
- 恶心 HP:0002018
- 瘫痪 HP:0003470
- 咽炎 HP:0025439
- 骨骼肌萎缩 HP:0003202
- 颈部僵硬 HP:0025258
- 呕吐 HP:0002013
偶见 29–5%19
- 扁桃体缺如 HP:0030813
- 球麻痹 HP:0001283
- 球部体征 HP:0002483
- 颅神经麻痹 HP:0006824
- 运动减少 HP:0002374
- 吞咽困难 HP:0002015
- 发音困难 HP:0001618
- 肌束震颤 HP:0002380
- 呼吸肌疲劳性无力 HP:0030196
- 运动过多 HP:0002487
- 免疫缺陷 HP:0002721
- 日常生活活动障碍 HP:0031058
- 行走不能 HP:0002540
- 麻痹性肠梗阻 HP:0002590
- 下肢轻瘫 HP:0002385
- 感觉异常 HP:0003401
- 呼吸衰竭 HP:0002878
- 呼吸衰竭,需要辅助通气 HP:0004887
- 上肢肌无力 HP:0003484
罕见 <4–1%8
- 焦虑不安 HP:0000713
- 昏迷 HP:0001259
- 意识模糊 HP:0001289
- 高血压 HP:0000822
- 低血压 HP:0002615
- 血量减少性休克 HP:0031274
- 传染性脑炎 HP:0002383
- 易激惹 HP:0000737
外部标识与链接
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本页数据来源
- 疾病定义、同义词、基因、表型、流行病学:Orphanet(CC BY 4.0)
- 中文病名:Orphanet 中文包,冻结于 2020-06-01
- 表型中文标签:HPO 简体中文翻译(CHPO 上游成果)