滑膜肉瘤
Synovial sarcoma
定义 英文原文（暂无中文）
A rare soft tissue sarcoma characterized by palpable, slow-growing, deep-seated swellings, with or without pain or tenderness, affecting mostly children and young adults. Patients may have pain or joint contractures that precede swelling. Contrary to its name, lesions do not originate from intra-articular synovium, but from primitive mesenchymal cells. Majority of the lesions arise in the extremities, predominantly in the lower extremity, however can also occur in the head and neck region, trunk, lungs and pleura. Metastasis to the lungs, bone and regional lymph nodes can be observed. Increasing size, age and tumor grade are reported as negative predictive factors for both local disease recurrence and metastasis.
别名
滑膜肉瘤
基本事实
- 遗传方式
- 不适用
- 发病年龄
- 各年龄段
相关基因 3
| 基因 | 名称 | 关联类型 |
|---|---|---|
| SS18 | SS18 subunit of BAF chromatin remodeling complex | Part of a fusion gene in |
| SSX1 | SSX family member 1 | Part of a fusion gene in |
| SSX2 | SSX family member 2 | Part of a fusion gene in |
外部标识与链接
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本页数据来源
- 疾病定义、同义词、基因、表型、流行病学：Orphanet（CC BY 4.0）
- 中文病名：Orphanet 中文包，冻结于 2020-06-01
- 表型中文标签：HPO 简体中文翻译（CHPO 上游成果）