高原性肺水肿
High altitude pulmonary edema
定义 英文原文(暂无中文)
A rare pulmonary condition characterized by non-cardiogenic pulmonary edema occurring in otherwise healthy individuals within days of an ascent above 2500-3000 m. Early symptoms include exertional dyspnea, non-productive cough, chest tightness, and reduced exercise performance, followed by dyspnea at rest and possibly orthopnea, as well as gurgling in the chest and pink frothy sputum in advanced cases. Clinical signs are cyanosis, tachypnea, tachycardia, crackles or wheezing, and elevated body temperature (generally not exceeding 38.5°C). Signs of concomitant high-altitude cerebral edema may also be observed. Chest x-rays typically show patchy opacities predominantly in the right middle lobe.
别名
HAPE
基本事实
- 遗传方式
- 不适用
- 发病年龄
- 各年龄段
- 患病率
- 1-9 / 1 000 000(Europe)
临床表型 21
必现 100%2
- 低氧血症 HP:0012418
- 肺水肿 HP:0100598
极常见 99–80%1
- 呼吸困难 HP:0002094
常见 79–30%11
- 厌食症 HP:0002039
- 咳嗽 HP:0012735
- 肺啰音 HP:0030830
- 紫绀 HP:0000961
- 运动不耐受 HP:0003546
- 头痛 HP:0002315
- 白细胞增多症 HP:0001974
- 恶心和呕吐 HP:0002017
- 肺部模糊影 HP:0031457
- 睡眠异常 HP:0002360
- 心动过速 HP:0001649
偶见 29–5%6
- 痰液异常 HP:0032016
- 胸痛 HP:0100749
- 发热 HP:0001945
- 端坐式呼吸 HP:0012764
- 呼吸过速 HP:0002789
- 眩晕 HP:0002321
罕见 <4–1%1
- 咯血 HP:0002105
外部标识与链接
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本页数据来源
- 疾病定义、同义词、基因、表型、流行病学:Orphanet(CC BY 4.0)
- 中文病名:Orphanet 中文包,冻结于 2020-06-01
- 表型中文标签:HPO 简体中文翻译(CHPO 上游成果)