土拉杆菌病
Tularemia
ORPHA:3392疾病
定义 英文原文（暂无中文）
A rare bacterial infectious disease caused by Francisella tularensis and characterized by six major clinical presentations: ulceroglandular, glandular, oropharyngeal, oculoglandular, pneumonic, or typhoidal, depending on the route of infection. Early flu-like symptoms are common to all forms and are accompanied/followed by either a skin inoculation ulcer with localized lymphadenopathy; isolated lymphadenopathy; chronic pharyngitis with cervical lymphadenopathy; conjunctivitis with localized lymphadenopathy; lung involvement; severe systemic disease with neurological symptoms.
基本事实
- 遗传方式
- 不适用
- 发病年龄
- 各年龄段
- 患病率
- <1 / 1 000 000（United Kingdom）
临床表型 38
常见 79–30%10
- 关节疼痛 HP:0002829
- 虚弱 HP:0025406
- 寒栗 HP:0025143
- 发热 HP:0001945
- 头痛 HP:0002315
- 循环抗体水平升高 HP:0010702
- 白细胞增多症 HP:0001974
- 肌痛 HP:0003326
- 肺炎 HP:0002090
- 心动过速 HP:0001649
偶见 29–5%14
- 肺胸部影像学异常 HP:0031983
- 贫血 HP:0001903
- 颈部淋巴结病变 HP:0025289
- 咳嗽 HP:0012735
- 局限性皮损 HP:0011355
- 淋巴结肿大 HP:0002716
- 颈痛 HP:0030833
- 口腔溃疡 HP:0000155
- 咽炎 HP:0025439
- 胸腔积液 HP:0002202
- 肺浸润 HP:0002113
- 呼吸窘迫 HP:0002098
- 皮疹 HP:0000988
- 血小板减少症 HP:0001873
罕见 <4–1%14
- 鼻咽部腺样体形态异常 HP:3000033
- 神经系统异常 HP:0000707
- 非典型行为 HP:0000708
- 脑脓肿 HP:0030049
- 意识模糊 HP:0001289
- 结膜充血 HP:0030953
- 结膜炎 HP:0000509
- 皮肤脓肿 HP:0031292
- 结节性红斑 HP:0012219
- 眼睛的炎性异常 HP:0100533
- 纵膈淋巴结病 HP:0100721
- 脑膜炎 HP:0001287
- 眼痛 HP:0200026
- 中耳炎 HP:0000388
外部标识与链接
OrphanetMONDO:0018077GARD:396ICD-10 A21.0、A21.1、A21.2、A21.3ICD-11 1B94、1B94.0、1B94.YClinicalTrials.gov 检索
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本页数据来源
- 疾病定义、同义词、基因、表型、流行病学：Orphanet（CC BY 4.0）
- 中文病名：Orphanet 中文包，冻结于 2020-06-01
- 表型中文标签：HPO 简体中文翻译（CHPO 上游成果）