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眉部瘢痕性红斑

Ulerythema ophryogenesis

ORPHA:3406疾病

定义 英文原文(暂无中文)

Ulerythema ophryogenesis is characterised by inflammatory keratotic papules occurring on the face, which may be followed by scars, atrophy and alopecia. Prevalence is unknown but the disease, affecting mainly children and young adults, is rare. Erythema with mild hyperkeratosis of the hair follicles resulting in rough papules is observed on the cheeks and lateral aspects of the eyebrows. The disorder occasionally extends to the adjacent scalp, ears and forehead and rarely to the extensor surfaces of the limbs. Symptoms regress with age, although loss of the lateral aspects of the eyebrows can occur. Many cases occur sporadically; autosomal dominant inheritance has also been reported. There is no particular treatment, but patients should avoid sun exposure without UV protection.

基本事实

遗传方式
常染色体显性、不适用
发病年龄
儿童期

临床表型 14

极常见 99–80%6

  • 红色丘疹 HP:0030350
  • 面部红斑 HP:0001041
  • 克尔里病,贯穿性角化过度病 HP:0007502
  • 角化过度性丘疹 HP:0045059
  • 毛囊角化症 HP:0032152
  • 眉尖稀疏 HP:0005338

常见 79–30%5

  • 面颊形态异常 HP:0004426
  • 下巴异常 HP:0000306
  • 前额异常 HP:0000290
  • 皮肤萎缩 HP:0004334
  • 干性皮肤 HP:0000958

偶见 29–5%3

  • 痤疮 HP:0001061
  • 接触性皮炎 HP:0032282
  • 流产 HP:0005268

外部标识与链接

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本页数据来源

  • 疾病定义、同义词、基因、表型、流行病学:Orphanet(CC BY 4.0)
  • 中文病名:Orphanet 中文包,冻结于 2020-06-01
  • 表型中文标签:HPO 简体中文翻译(CHPO 上游成果)