葡萄球菌坏死性肺炎
Staphylococcal necrotizing pneumonia
ORPHA:36238疾病
定义 英文原文（暂无中文）
Staphylococcal necrotizing pneumonia is a rare, bacterial, pulmonary infectious disease, caused by a Panton-Valentine leukocidin-producing Staphylococcus aureus strain, characterized by severe respiratory failure, extensive, rapidly progressing pneumonia and hemorrhagic lung necrosis. Patients typically present with influenza-like symptoms, such as fever, cough, and chest pain, as well as hemoptysis, hypotension, leukopenia, and severe respiratory symptoms that rapidly evolve to acute respiratory distress syndrome and septic shock. High mortality is associated.
基本事实
- 遗传方式
- 不适用
- 发病年龄
- 儿童期
临床表型 38
极常见 99–80%9
- 咳嗽 HP:0012735
- 呼吸困难 HP:0002094
- 红细胞沉降速度升高 HP:0003565
- 发热 HP:0001945
- 白细胞增多症 HP:0001974
- 肺炎 HP:0002090
- 呼吸窘迫 HP:0002098
- 重度感染 HP:0032169
- 呼吸过速 HP:0002789
常见 79–30%13
- 急性感染性肺炎 HP:0011949
- 菌血症 HP:0031864
- 胸痛 HP:0100749
- C-反应蛋白水平升高 HP:0011227
- 低血压 HP:0002615
- 低氧血症 HP:0012418
- 血液降钙素原水平升高 HP:0032308
- 中性粒细胞增多症 HP:0011897
- 干咳 HP:0031246
- 肺实变 HP:0032177
- 胸腔积液 HP:0002202
- 脓胸 HP:0011919
- 呼吸衰竭 HP:0002878
偶见 29–5%14
- 痰液异常 HP:0032016
- 意识模糊 HP:0001289
- 坏疽 HP:0100758
- 咯血 HP:0002105
- 免疫缺陷 HP:0002721
- 昏睡 HP:0001254
- 白细胞减少症 HP:0001882
- 咽炎 HP:0025439
- 气胸 HP:0002107
- 肺浸润 HP:0002113
- 肺气肿 HP:0025419
- 脓毒症 HP:0100806
- 颤抖 HP:0025144
- 休克 HP:0031273
罕见 <4–1%2
- 酗酒 HP:0030955
- 糖尿病 HP:0000819
外部标识与链接
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本页数据来源
- 疾病定义、同义词、基因、表型、流行病学：Orphanet（CC BY 4.0）
- 中文病名：Orphanet 中文包，冻结于 2020-06-01
- 表型中文标签：HPO 简体中文翻译（CHPO 上游成果）