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阴茎鳞状细胞癌

Squamous cell carcinoma of the penis

ORPHA:398058疾病

定义 英文原文(暂无中文)

A rare urogenital tumor characterized by origin from squamous epithelial cells of the penis, most commonly the glans or inner surface of the prepuce. Macroscopically, the tumors can appear either papillary or flat and ulcerating. Histological subtypes include usual squamous cell carcinoma as the most common type, as well as basaloid, warty, verrucous, papillary, and mixed carcinomas. Patients may initially be asymptomatic but present with itching, bleeding, discharge, foul odor, and pain, as the disease progresses. Regional lymph node involvement is common, while distant metastases occur only late in the disease. Risk factors include HPV infection, smoking, poor hygiene, and HIV infection. Neonatal circumcision is implicated as strongly protective.

别名

阴茎鳞状细胞癌

基本事实

遗传方式
不适用
发病年龄
老年期
患病率
1-9 / 1 000 000(Europe)

外部标识与链接

OrphanetMONDO:0018352ICD-10 C60.0、C60.1、C60.2、C60.8ICD-11 2C81.0ClinicalTrials.gov 检索

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本页数据来源

  • 疾病定义、同义词、基因、表型、流行病学:Orphanet(CC BY 4.0)
  • 中文病名:Orphanet 中文包,冻结于 2020-06-01
  • 表型中文标签:HPO 简体中文翻译(CHPO 上游成果)