蛇咬中毒
Snakebite envenomation
ORPHA:449285疾病
定义 英文原文（暂无中文）
A rare disorder due to poisoning caused by toxins in the bite of a venomous snake. Envenoming can also be caused by spraying of venom into the eyes. Depending on venom composition and other factors, consequences range from local tissue damage to potentially life-threatening systemic effects. Severe manifestations include paralysis, bleeding disorders, kidney failure, or permanent disability and limb amputation due to severe local tissue destruction. Children may suffer more severe effects because of their lower body mass. Immediate medical attention, in particular administration of antivenom, is critical.
基本事实
- 遗传方式
- 不适用
- 发病年龄
- 各年龄段
- 患病率
- 1-9 / 100 000（Europe）
临床表型 34
极常见 99–80%1
- 水肿 HP:0000969
常见 79–30%4
- 瘀斑 HP:0031364
- 红斑 HP:0010783
- 局限性皮损 HP:0011355
- 疼痛 HP:0012531
偶见 29–5%15
- 异常出血 HP:0001892
- 凝血异常 HP:0001928
- 神经系统异常 HP:0000707
- 脑缺血 HP:0002637
- 低纤维蛋白原血症 HP:0011900
- 颅内出血 HP:0002170
- 肌纤维坏死 HP:0003713
- 瘫痪 HP:0003470
- 假性球麻痹 HP:0007024
- 横纹肌溶解症 HP:0003201
- 言语表达困难 HP:0009088
- 卒中 HP:0001297
- 心动过速 HP:0001649
- 血小板减少症 HP:0001873
- 呕吐 HP:0002013
罕见 <4–1%14
- 急性肾损伤 HP:0001919
- 血管性水肿 HP:0100665
- 心源性休克 HP:0030149
- 腹泻 HP:0002014
- 弥漫性血管内凝血 HP:0005521
- 鼻衄 HP:0000421
- 牙龈出血 HP:0000225
- 低钠血症 HP:0002902
- 垂体功能减退 HP:0040075
- 低血压 HP:0002615
- 心肌梗死 HP:0001658
- 神经肌肉源性吞咽困难 HP:0002068
- 呼吸衰竭 HP:0002878
- 呼吸肌麻痹 HP:0002203
外部标识与链接
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本页数据来源
- 疾病定义、同义词、基因、表型、流行病学：Orphanet（CC BY 4.0）
- 中文病名：Orphanet 中文包，冻结于 2020-06-01
- 表型中文标签：HPO 简体中文翻译（CHPO 上游成果）