急性放射病综合征
Acute radiation syndrome
定义 英文原文（暂无中文）
A rare radiation-induced disorder resulting from whole body exposure to large doses of penetrating radiation (>0.7 Gray) within a very short period of time (usually minutes) and characterized by bone marrow syndrome with pancytopenia (mild symptoms of which may occur already at 0.3 Gray), gastrointestinal syndrome resulting in mostly fatal infection, dehydration, and electrolyte imbalance (occurring at doses >10 Gray), and cardiovascular/central nervous system syndrome with watery diarrhea, convulsions, coma, and death within three days of exposure (occurring at doses >50 Gray). The syndrome develops in four clinical stages (prodromal/latent/manifest illness/recovery or death) of variable duration.
别名
急性放射病
基本事实
- 遗传方式
- 不适用
- 发病年龄
- 各年龄段
- 患病率
- 1-9 / 1 000 000（Europe）
临床表型 24
极常见 99–80%1
- 皮肤萎缩 HP:0004334
常见 79–30%12
- 异常出血 HP:0001892
- 腹泻 HP:0002014
- 发热 HP:0001945
- 头痛 HP:0002315
- 皮肤色素沉着 HP:0000953
- 皮肤色素减退 HP:0001010
- 淋巴细胞减少症 HP:0001888
- 肌无力 HP:0001324
- 皮肤脱屑 HP:0040189
- 毛细血管扩张 HP:0001009
- 血小板减少症 HP:0001873
- 呕吐 HP:0002013
偶见 29–5%11
- 白内障 HP:0000518
- 疲乏 HP:0012378
- 粒细胞减少症 HP:0001913
- 角化过度 HP:0000962
- 低血压 HP:0002615
- 皮肤炎症反应 HP:0011123
- 间质性肺炎 HP:0006515
- 意识丧失 HP:0007185
- 癫痫发作 HP:0001250
- 皮肤溃疡 HP:0200042
- 眩晕 HP:0002321
外部标识与链接
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本页数据来源
- 疾病定义、同义词、基因、表型、流行病学：Orphanet（CC BY 4.0）
- 中文病名：Orphanet 中文包，冻结于 2020-06-01
- 表型中文标签：HPO 简体中文翻译（CHPO 上游成果）