掌跖角化病

定义 英文原文（暂无中文）

A rare, isolated, diffuse palmoplantar keratoderma disorder characterized by red-yellow, moderate to severe hyperkeratosis of the palms and soles, extending to the dorsal aspects of the hands, feet and/or wrists and involving the skin over the Achilles' tendon (transgrediens), gradually worsening with age (progrediens) to include patchy hyperkeratosis over the shins, knees, elbows and, sometimes, skin flexures. Hyperhidrosis is usually associated. Histologically, either epidermolytic or nonepidermolytic changes may be seen.

别名

逾越型和进育型掌跖角化病

基本事实

发病年龄

儿童期

患病率

<1 / 1 000 000

临床表型 18

外部标识与链接