鼻腔和鼻旁窦鳞状细胞癌
Squamous cell carcinoma of the nasal cavity and paranasal sinuses
定义 英文原文（暂无中文）
A rare head and neck tumor characterized by a malignant epithelial neoplasm most commonly arising in the maxillary sinus or nasal cavity, occurring as a keratinizing, a non-keratinizing, or a spindle cell (sarcomatoid) type. Patients may present with nasal obstruction, epistaxis, rhinorrhea, swelling, or (at more advances stages) with facial pain and/or paralysis, diplopia, and proptosis. Patients with paranasal sinus tumors present later and at a higher stage than patients with nasal cavity carcinomas. Risk factors are smoking and industrial exposures. High-risk HPV is most frequently associated with the non-keratinizing type.
别名
Squamous cell carcinoma of the nasal cavity and sinuses
基本事实
- 遗传方式
- 不适用
- 发病年龄
- 成年期、老年期
- 患病率
- 1-9 / 1 000 000
相关基因 3
| 基因 | 名称 | 关联类型 |
|---|---|---|
| PTEN | phosphatase and tensin homolog | Disease-causing somatic mutation(s) in |
| ING1 | inhibitor of growth family member 1 | Disease-causing somatic mutation(s) in |
| TNFRSF10B | TNF receptor superfamily member 10b | Major susceptibility factor in |
外部标识与链接
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本页数据来源
- 疾病定义、同义词、基因、表型、流行病学：Orphanet（CC BY 4.0）
- 中文病名：Orphanet 中文包，冻结于 2020-06-01
- 表型中文标签：HPO 简体中文翻译（CHPO 上游成果）