唇部鳞状细胞癌
Squamous cell carcinoma of the lip
ORPHA:502366疾病
定义 英文原文（暂无中文）
A rare head and neck tumor characterized by a firm infiltrative neoplasm with squamous differentiation, most commonly arising at the vermilion border of the lower lip. Patients present with a usually asymptomatic lesion of variable appearance, such as ulceration, a focus of whitish thickening, a dry atrophic area, or an area of persistent chapping and localized flaking and crusting. Carcinomas of the lower lip tend to progress slowly (as opposed to those of the upper lip). Invasion of adjacent structures, including perineural spread, is typical, with a variable rate of metastasis, depending on the location.
基本事实
- 遗传方式
- 不适用
- 发病年龄
- 成年期、老年期
- 患病率
- 1-9 / 100 000
相关基因 3
| 基因 | 名称 | 关联类型 |
|---|---|---|
| PTEN | phosphatase and tensin homolog | Disease-causing somatic mutation(s) in |
| ING1 | inhibitor of growth family member 1 | Disease-causing somatic mutation(s) in |
| TNFRSF10B | TNF receptor superfamily member 10b | Major susceptibility factor in |
外部标识与链接
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本页数据来源
- 疾病定义、同义词、基因、表型、流行病学：Orphanet（CC BY 4.0）
- 中文病名：Orphanet 中文包，冻结于 2020-06-01
- 表型中文标签：HPO 简体中文翻译（CHPO 上游成果）