急性髓性白血病
Acute myeloid leukemia
ORPHA:519疾病组
定义 英文原文（暂无中文）
A group of neoplasms arising from precursor cells committed to the myeloid cell-line differentiation. All of them are characterized by clonal expansion of myeloid blasts. They manifest by fever, pallor, anemia, hemorrhages and recurrent infections.
别名
急性髓性白血病
基本事实
- 发病年龄
- 各年龄段
- 患病率
- 1-9 / 100 000
相关基因 12来自下位疾病
Orphanet 未在本条目上直接标注致病基因。下表由本组所属的下位疾病汇总而来，「来源条目」列给出基因实际标注在哪一个 ORPHA 条目上。
| 基因 | 名称 | 来源条目 |
|---|---|---|
| ASXL1 | ASXL transcriptional regulator 1 | ORPHA:86845 |
| CEBPA | CCAAT enhancer binding protein alpha | ORPHA:319465 |
| DNMT3A | DNA methyltransferase 3 alpha | ORPHA:86845 |
| ERCC6L2 | ERCC excision repair 6 like 2 | ORPHA:319465 |
| FLT3 | fms related receptor tyrosine kinase 3 | ORPHA:98832 |
| GATA1 | GATA binding protein 1 | ORPHA:99887 |
| IDH1 | isocitrate dehydrogenase (NADP(+)) 1 | ORPHA:86845 |
| IDH2 | isocitrate dehydrogenase (NADP(+)) 2 | ORPHA:86845 |
| KIT | KIT proto-oncogene, receptor tyrosine kinase | ORPHA:98834 |
| NPM1 | nucleophosmin 1 | ORPHA:402026 |
| TET2 | tet methylcytosine dioxygenase 2 | ORPHA:86845 |
| TGM6 | transglutaminase 6 | ORPHA:319465 |
外部标识与链接
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本页数据来源
- 疾病定义、同义词、基因、表型、流行病学：Orphanet（CC BY 4.0）
- 中文病名：Orphanet 中文包，冻结于 2020-06-01
- 表型中文标签：HPO 简体中文翻译（CHPO 上游成果）