Conjunctival malignant melanoma
定义 英文原文（暂无中文）
A rare eye tumor characterized by a flat to nodular conjunctival mass with variable pigmentation. It can arise in any part of the conjunctiva but most often presents on the bulbar surface, near the limbus. Invasion of corneal tissue, eyelid margin, sclera or orbit may occur in advanced tumors. Metastatic spread most commonly involves regional lymph nodes or the lung, liver, and brain. Essential diagnostic criteria are stromal invasion and severe cytological and architectural atypia exceeding those expected in a naevus. Desirable criteria are demonstration of melanocytic markers by immunohistochemistry, pagetoid growth, mitotic activity, invasion into cornea or skin, ulceration, and tumor necrosis.
别名
Conjunctival melanoma
基本事实
- 遗传方式
- 不适用
- 患病率
- <1 / 1 000 000
外部标识与链接
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本页数据来源
- 疾病定义、同义词、基因、表型、流行病学：Orphanet（CC BY 4.0）
- 中文病名：Orphanet 中文包，冻结于 2020-06-01；本条目在该版本中无中文名
- 表型中文标签：HPO 简体中文翻译（CHPO 上游成果）