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急性双侧虹膜色素脱失

Bilateral acute depigmentation of the iris

ORPHA:69736疾病

定义 英文原文(暂无中文)

Bilateral acute depigmentation of the iris (BADI) is characterized by acute onset of bilateral iris depigmentation, pigment dispersion in the anterior chamber, and heavy pigment deposition in the anterior chamber angle. Patients typically present with acute and usually severe photophobia, blurred vision, red eye, and ocular discomfort or pain with a usually self-limiting clinical course. Cases often occur after a flu-like illness, upper respiratory tract infection, and after the use of oral moxifloxacin. When associated with iris epithelial depigmentation, iris transillumination defects and atonic/mydriatic pupil, the condition is referred to as bilateral acute iris transillumination (BAIT) which has an increased risk of severe intractable rise in intraocular pressure.

别名

BADI

基本事实

遗传方式
未知
发病年龄
成年期
患病率
<1 / 1 000 000

临床表型 10

必现 100%2

  • 虹膜异常色素沉着 HP:0008034
  • 虹膜基质发育不全 HP:0007990

常见 79–30%5

  • 前房形态异常 HP:0000593
  • 角膜内皮形态异常 HP:0011488
  • 眼部形态异常 HP:0012372
  • 眼痛 HP:0200026
  • 畏光 HP:0000613

偶见 29–5%3

  • 虹膜色素播散 HP:0012634
  • 小梁网色素沉积 HP:0012631
  • 复发性上呼吸道感染 HP:0002788

外部标识与链接

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本页数据来源

  • 疾病定义、同义词、基因、表型、流行病学:Orphanet(CC BY 4.0)
  • 中文病名:Orphanet 中文包,冻结于 2020-06-01
  • 表型中文标签:HPO 简体中文翻译(CHPO 上游成果)