疣性角化不良瘤
Warty dyskeratoma
ORPHA:69745疾病
定义 英文原文（暂无中文）
A rare, benign, epidermal disease characterized by a solitary, asymptomatic, verrucous, skin-coloured to red-brown papule or nodule, which contains a central pore and keratotic plug, occuring most frequently on the scalp, face and neck (rarely, in the mouth, under the nail plate or on the mons pubis). Occasionally, lesions may be multiple and/or pruritic. Histologically, a well-circumscribed, cup-shaped, keratin-filled invagination, with prominent acantholytic dyskeratosis, suprabasilar clefts and villi projecting into the clefts, is observed.
别名
滤泡角膜瘤
基本事实
- 遗传方式
- 未知
- 发病年龄
- 成年期
临床表型 19
极常见 99–80%4
- 毛囊周围形态异常 HP:0031285
- 皮肤棘层松解 HP:0100792
- 表皮增厚 HP:0011368
- 局限性皮损 HP:0011355
常见 79–30%6
- 颈部异常 HP:0000464
- 头皮形态异常 HP:0001965
- 肢端角化症 HP:0200016
- 红色丘疹 HP:0030350
- 肤色丘疹 HP:0025512
- 脐状结界 HP:0025103
偶见 29–5%2
- 口腔粘膜局灶性上皮增生 HP:0410340
- 口腔黏膜结节 HP:0031445
罕见 <4–1%7
- 异常出血 HP:0001892
- 指甲形态异常 HP:0001231
- 硬腭形态异常 HP:0100737
- 牙槽嵴形态异常 HP:0006477
- 大阴唇形态异常 HP:0012881
- 舌瘤 HP:0100648
- 外阴肿瘤 HP:0030416
外部标识与链接
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本页数据来源
- 疾病定义、同义词、基因、表型、流行病学：Orphanet（CC BY 4.0）
- 中文病名：Orphanet 中文包，冻结于 2020-06-01
- 表型中文标签：HPO 简体中文翻译（CHPO 上游成果）