移植后淋巴增殖性疾病
Post-transplant lymphoproliferative disease
定义 英文原文（暂无中文）
A group of rare immunodeficiency-associated lymphoproliferative disorders characterized by lymphoid or plasmacytic proliferations developing in the context of immunosuppression in a recipient of a solid organ or stem cell allograft. The group includes non-destructive post-transplant lymphoproliferative disorders (PTLDs), polymorphic PTLD, monomorphic PTLDs, and classic Hodgkin lymphoma PTLD. Patients may have more than one type of PTLD in a single or in different locations. The most commonly involved sites are lymph nodes, gastrointestinal tract, lungs, and liver, although the disease may occur almost anywhere in the body. In solid organ transplant recipients, PTLD may also involve the allograft.
别名
PTLD
基本事实
- 遗传方式
- 不适用
- 发病年龄
- 各年龄段
- 患病率
- 1-5 / 10 000（Europe）
临床表型 16
常见 79–30%10
- 声音异常 HP:0001608
- 疲乏 HP:0012378
- 发热 HP:0001945
- 淋巴结肿大 HP:0002716
- 全身乏力不适 HP:0033834
- 盗汗 HP:0030166
- 咽痛 HP:0033050
- 食欲不振 HP:0004396
- 打鼾 HP:0025267
- 体重减轻 HP:0001824
偶见 29–5%6
- 腹痛 HP:0002027
- 腹泻 HP:0002014
- 胃肠道出血 HP:0002239
- 肝炎 HP:0012115
- 低蛋白血症 HP:0003073
- 肺结节 HP:0033608
外部标识与链接
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本页数据来源
- 疾病定义、同义词、基因、表型、流行病学：Orphanet（CC BY 4.0）
- 中文病名：Orphanet 中文包，冻结于 2020-06-01
- 表型中文标签：HPO 简体中文翻译（CHPO 上游成果）