小细胞肺癌
Small cell lung cancer
ORPHA:70573疾病
定义 英文原文（暂无中文）
Small cell lung cancer (SCLC) is a highly aggressive malignant neoplasm, accounting for 10-15% of lung cancer cases, characterized by rapid growth, and early metastasis. SCLC usually manifests as a large hilar mass with bulky mediastinal lymphadenopathy presenting clinically with chest pain, persistent cough, dyspnea, wheezing, hoarseness, hemoptysis, loss of appetite, weight loss, and neurological and endocrine paraneoplastic syndromes. SCLC is primarily reported in elderly people with a history of long-term tobacco exposure.
别名
SCLC
基本事实
- 遗传方式
- 不适用
- 发病年龄
- 成年期
- 患病率
- 1-5 / 10 000（Europe）
相关基因 3
| 基因 | 名称 | 关联类型 |
|---|---|---|
| RB1 | RB transcriptional corepressor 1 | Disease-causing somatic mutation(s) in |
| TP53 | tumor protein p53 | Disease-causing somatic mutation(s) in |
| TP73 | tumor protein p73 | Disease-causing somatic mutation(s) in |
外部标识与链接
发现这一页有错误？告诉我 · 邮件主题会自动带上本页的 ORPHA 编号
本页数据来源
- 疾病定义、同义词、基因、表型、流行病学：Orphanet（CC BY 4.0）
- 中文病名：Orphanet 中文包，冻结于 2020-06-01
- 表型中文标签：HPO 简体中文翻译（CHPO 上游成果）