鼠疫
Plague
定义 英文原文（暂无中文）
A rare zoonotic disease characterized by life-threatening, highly contagious and rapidly progressing infection caused by the Gram-negative bacterium Yersinia pestis, affecting rodents, and transmitted to human accidentally. It manifests differently depending on the route of infection. Bubonic plague results from the bite of an infected rodent flea. Pneumonic plague, less frequent but more dangerous, may arise through inhalation of infectious droplets or spread of bubonic plague to the lungs. Septicemic plague occurs from dissemination into the bloodstream, either as a primary infection or as a complication of bubonic or pneumonic forms, leading to disseminated intravascular coagulation, necrosis, and multi-organ failure.
别名
耶尔森菌病
基本事实
- 发病年龄
- 各年龄段
- 患病率
- 1-9 / 100 000（Europe）
临床表型 55
极常见 99–80%3
- 疲乏 HP:0012378
- 发热 HP:0001945
- 淋巴结炎 HP:0002840
常见 79–30%17
- 皮肤的异常起疱 HP:0008066
- 厌食症 HP:0002039
- 焦虑 HP:0000739
- 菌血症 HP:0031864
- 痈 HP:0020084
- 胸痛 HP:0100749
- 寒栗 HP:0025143
- 结膜充血 HP:0030953
- 谵妄 HP:0031258
- 干性皮肤 HP:0000958
- 头痛 HP:0002315
- 肝脏肿大 HP:0002240
- 局限性皮损 HP:0011355
- 意识下降 HP:0004372
- 皮肤溃疡 HP:0200042
- 脾肿大 HP:0001744
- 心动过速 HP:0001649
偶见 29–5%29
- 腹痛 HP:0002027
- 异常出血 HP:0001892
- 肘部异常 HP:0009811
- 急性感染性肺炎 HP:0011949
- 心律失常 HP:0011675
- 关节疼痛 HP:0002829
- 便血 HP:0025085
- 嘴唇皲裂 HP:0040181
- 昏迷 HP:0001259
- 抑郁 HP:0000716
- 腹泻 HP:0002014
- 水肿 HP:0000969
- 肠系膜淋巴结肿大 HP:0025043
- 小肠结肠炎 HP:0004387
- 结节性红斑 HP:0012219
- 舌炎 HP:0000206
- 听力受损 HP:0000365
- 呕血 HP:0002248
- 咯血 HP:0002105
- 低血压 HP:0002615
- 回肠炎 HP:0032564
- 大肠炎症 HP:0002037
- 瞳孔散大 HP:0011499
- 呼吸窘迫 HP:0002098
- 脓毒症 HP:0100806
- 皮疹 HP:0000988
- 言语不清 HP:0001350
- 步态不稳 HP:0002317
- 呕吐 HP:0002013
罕见 <4–1%6
- 关节炎 HP:0001369
- 心内膜炎 HP:0100584
- 眼睛的炎性异常 HP:0100533
- 脑膜炎 HP:0001287
- 肌无力 HP:0001324
- 咽炎 HP:0025439
外部标识与链接
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本页数据来源
- 疾病定义、同义词、基因、表型、流行病学：Orphanet（CC BY 4.0）
- 中文病名：Orphanet 中文包，冻结于 2020-06-01
- 表型中文标签：HPO 简体中文翻译（CHPO 上游成果）