肺孢子虫病
Pneumocystosis
ORPHA:723疾病
定义 英文原文（暂无中文）
Human pneumocystosis is caused by an infectious agent, which (after recent nomenclature and taxonomy revisions) is now classed as the fungus Pneumocystis jiroveci. The prevalence is unknown. Pneumocystis jiroveci is an opportunistic infectious agent, developing in immunosuppressed patients. It is an air-borne infection, localised to the lungs. However, extrapulmonary involvement is seen in AIDS patients. The disease manifests progressively with coughing, respiratory problems (dyspnea) and fever, followed by acute respiratory insufficiency and death within a few weeks in untreated cases. The most reliable diagnostic method is bronchoalveolar lavage. The treatment of choice is cotrimoxazole.
基本事实
- 遗传方式
- 不适用
- 发病年龄
- 各年龄段
临床表型 23
极常见 99–80%5
- 急性感染性肺炎 HP:0011949
- 呼吸困难 HP:0002094
- 发热 HP:0001945
- 低氧血症 HP:0012418
- 肺孢子菌肺炎 HP:0020102
常见 79–30%12
- 中性粒细胞数量异常 HP:0011991
- 肺部HRCT可见囊状与毛玻璃样结构 HP:0025395
- 劳力性呼吸困难 HP:0002875
- 免疫缺陷 HP:0002721
- 循环抗体水平升高 HP:0010702
- 间质性肺炎 HP:0006515
- 干咳 HP:0031246
- 胸腔积液 HP:0002202
- 呼吸衰竭 HP:0002878
- 呼吸衰竭，需要辅助通气 HP:0004887
- 呼吸功能不全 HP:0002093
- 体重减轻 HP:0001824
偶见 29–5%6
- 血源性传染病原体 HP:0031863
- 慢性口腔念珠菌病 HP:0009098
- 乳酸脱氢酶活性增高 HP:0025435
- 多发肺囊肿 HP:0005948
- 肿瘤 HP:0002664
- 肺实变 HP:0032177
外部标识与链接
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本页数据来源
- 疾病定义、同义词、基因、表型、流行病学：Orphanet（CC BY 4.0）
- 中文病名：Orphanet 中文包，冻结于 2020-06-01
- 表型中文标签：HPO 简体中文翻译（CHPO 上游成果）