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复杂性局部疼痛综合征

Complex regional pain syndrome

ORPHA:83452疾病

定义 英文原文(暂无中文)

A rare neurologic disease characterized by persistent pain that is disproportionate to the inciting event. The pain is regional, usually affecting a limb with a distal predominance, and may occur spontaneously or be stimulus-induced. It is associated with sensory disturbances, vasomotor abnormalities (including changes in skin color and temperature), sudomotor abnormalities, edema, and motor or trophic changes. Symptoms often develop following trauma, fractures, immobilization, surgery, or nerve injury, and their severity and clinical presentation can vary considerably among patients.

别名

Sudeck's atrophy、Causalgia、Reflex sympathetic dystrophy、Algodystrophy、Algoneurodystrophy

基本事实

遗传方式
不适用
发病年龄
各年龄段
患病率
1-5 / 10 000(Netherlands)

临床表型 12

极常见 99–80%1

  • 肢体疼痛 HP:0009763

常见 79–30%11

  • 头发生长异常 HP:0040170
  • 痛觉过敏 HP:0012533
  • 干性皮肤 HP:0000958
  • 感觉障碍 HP:0012534
  • 上肢水肿 HP:0010742
  • 红斑 HP:0010783
  • 不自主运动 HP:0004305
  • 下肢水肿 HP:0010741
  • 甲生长缓慢 HP:0008383
  • 躯体感觉异常 HP:0003474
  • 与疼痛相关的营养改变 HP:0010834

外部标识与链接

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本页数据来源

  • 疾病定义、同义词、基因、表型、流行病学:Orphanet(CC BY 4.0)
  • 中文病名:Orphanet 中文包,冻结于 2020-06-01
  • 表型中文标签:HPO 简体中文翻译(CHPO 上游成果)