功能性促性腺腺瘤
Functioning gonadotropic adenoma
定义 英文原文（暂无中文）
Functioning gonadotropic adenoma is a very rare pituitary tumor, macroscopically characterized by a soft, well vascularized, variable sized adenoma, with occasional areas of hemorrage or necrosis, that secretes biologically active gonadotropins. In addition to common neurological signs due to mass effect (headache and/or visual field deterioration), additional clinical manifestations include menstrual irregularities (secondary amenorrhea, oligomenorhea or severe menorrhagia), galactorrhea, infertility or ovarian hyperstimulation syndrome (in premenopausal women), testicular enlargement and, occasionally, hypogonadism (in men) and isosexual precocious puberty (in children).
别名
功能性垂体促性腺腺瘤
基本事实
- 发病年龄
- 成年期
临床表型 34
必现 100%1
- 垂体促性腺激素腺瘤 HP:0011759
常见 79–30%10
- 催乳素水平异常 HP:0040086
- 月经周期异常 HP:0000140
- 垂体前叶功能减退症 HP:0000830
- 女性性欲降低 HP:0030018
- 疲乏 HP:0012378
- 阳痿 HP:0000802
- 血清睾酮水平增高 HP:0030088
- 不孕症/不育症 HP:0000789
- 视野缺损 HP:0001123
- 视觉障碍 HP:0000505
偶见 29–5%23
- 第二性征毛发异常 HP:0009888
- 促肾上腺皮质激素不足 HP:0011748
- 闭经 HP:0000141
- 腹水 HP:0001541
- 中枢性尿崩症 HP:0000863
- 生长激素刺激试验反应降低 HP:0000824
- 深静脉血栓形成 HP:0002625
- 青春期发育延迟 HP:0000823
- 骨成熟延迟 HP:0002750
- 增大的多囊卵巢 HP:0008675
- 溢乳 HP:0100829
- 头痛 HP:0002315
- 脑积水 HP:0000238
- 促性腺激素水平升高 HP:0000837
- 同性性早熟 HP:0008236
- 青春期后大睾丸 HP:0002050
- 动眼神经麻痹 HP:0012246
- 少精症 HP:0000798
- 骨质减少 HP:0000938
- 骨质疏松 HP:0000939
- 卵巢囊肿 HP:0000138
- 全垂体功能减退 HP:0000871
- 垂体性甲状腺功能减退症 HP:0008245
外部标识与链接
发现这一页有错误？告诉我 · 邮件主题会自动带上本页的 ORPHA 编号
本页数据来源
- 疾病定义、同义词、基因、表型、流行病学：Orphanet（CC BY 4.0）
- 中文病名：Orphanet 中文包，冻结于 2020-06-01
- 表型中文标签：HPO 简体中文翻译（CHPO 上游成果）