慢性粒-单核细胞白血病
Chronic myelomonocytic leukemia
ORPHA:98823疾病
定义 英文原文（暂无中文）
A rare myelodysplastic/myeloproliferative neoplasm characterized by a spectrum of clinical, hematological, and morphological features, ranging from predominantly myelodysplastic to mainly myeloproliferative in nature, with blood monocytosis (> 1G/L, constituting > 10% of circulating leukocytes). Is it often associated with blood cytopenia and/or ''proliferative features'' (increased leukocyte counts, splenomegaly), with marrow dysplasia and risk of progression to acute myeloid leukemia (AML).
别名
CMML
基本事实
- 遗传方式
- 不适用
- 发病年龄
- 成年期
- 患病率
- 1-9 / 1 000 000
相关基因 3
| 基因 | 名称 | 关联类型 |
|---|---|---|
| ETV6 | ETS variant transcription factor 6 | Part of a fusion gene in |
| ASXL1 | ASXL transcriptional regulator 1 | Candidate gene tested in |
| SRSF2 | serine and arginine rich splicing factor 2 | Candidate gene tested in |
外部标识与链接
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本页数据来源
- 疾病定义、同义词、基因、表型、流行病学：Orphanet（CC BY 4.0）
- 中文病名：Orphanet 中文包，冻结于 2020-06-01
- 表型中文标签：HPO 简体中文翻译（CHPO 上游成果）